Ribosomal protein S2



Ribosomal protein S2 (RPS2) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. Its N-terminal is rich in Arg-Gly repeats and has two RGGF copies which are believed to be associated with nuclear localization and binding to RNA. In archaea the protein is called S2P (RPS2P). The images at the left and at the right correspond to one representative RPS2, i.e. the crystal structure of Ribosomal protein S2 from Escherichia coli (3kc4).

3D Structures of Ribosomal protein S2
Update June 2011

S2
1vi5, 1vi6 – RPS2P – Archaeoglobus fulgidus

S2 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oto - TtRPS2 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS2 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 - EcRPS2 in 30S ribosomal subunit - Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx - EcRPS2 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS2 in 30S ribosomal subunit+16S RRNA

1p87 - EcRPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S2 in small + large ribosomal subunit
1ml5 - EcRPS2 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S2 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S2 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp, 2i2p, 2i2u - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr- TtRPS2 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S2 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S2 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS2 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS2 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS2 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA

3i1q - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

2om7 – TtRPS2+TtRPS12+TtRPL1+ P-site tRNA+16S RRNA fragment+23S RRNA fragment

S2 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S2 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S2 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S2 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh, 2f4v, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4 - TtRPS2 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnw, 1hnx, 1hnz, 1fjg - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2quo, 2qow, 2qoy, 2qp0, 2z4k, 2z4m, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofyp, 3or9, 3ora - EcRPS2 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

3knj, 3knh - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knm, 3knn, 3kno - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S2 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S2 in small ribosomal subunit + elongation factor
2wri, 2wrk - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

2y0u, 2y0w, 2y0y, 2y10, 2y12, 2y14, 2y16, 2y18 - TtRPS2 in30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

3fih - EcRPS2 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3izv - EcRPS2 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw - EcRPS2 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS2 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

S2 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS2 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS2 in 30S ribosomal subunit+THX+IF+16S RRNA

S2 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS2 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS2 in 30S ribosomal subunit+protein Y+16S RRNA

1x18 – TtRPS2+TtRPS7+TtRPS11+TtRPS18+GTP-binding protein ERA+RNA fragments

S2 in small 40S ribosomal subunit
3jyv - TlRPS2 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus

2xzm, 2xzn - RPS2 in 40S ribosomal subunit+RACK1 – Tetrahymena thermophila

1s1h - yRPS2 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

3izb - yRPS2 in 40S ribosomal subunit+ RACK1 – Cryo-EM

3o2z, 3o30 - yRPS2 in 40S ribosomal subunit+ RACK1

3iz6 - RPS2 in 40S ribosomal subunit+RACK1 - wheat